A national overview of where psilocybin, MDMA, DMT, ibogaine, and ketamine stand in every US state. Federal Schedule I rules sit on top of everything below — but each state adds its own layer.
Most classic psychedelics are Schedule I under the federal Controlled Substances Act of 1970. That includes psilocybin, MDMA, DMT, LSD, ibogaine, mescaline, and 5-MeO-DMT.
Schedule I means the federal government treats these drugs as having no accepted medical use and high abuse potential. Possession is a federal crime, even in states that have decriminalized.
The big exception is ketamine. Ketamine is Schedule III and FDA-approved (as Spravato for treatment-resistant depression). It is legal and accessible in every state, by prescription.
The April 2026 Trump psychedelics executive order speeds up FDA review for psychedelic drugs. But it does not change any drug's federal schedule.
Every US state falls into one of four buckets. The tier system helps you see which states actually allow legal access versus those that only deprioritize enforcement.
State has a licensed, regulated framework for adults to legally use a psychedelic.
States: Oregon (Measure 109 psilocybin service centers, 2023) · Colorado (Prop 122 Natural Medicine Health Act, 2022)
State has passed pilot programs, city-level decrim, or has live legislation moving in 2025–2026.
States: California (SB 751 advancing), Massachusetts (5 cities decrim), Washington (Seattle decrim, pilot research bill), Michigan (4 cities decrim), New York (Albany research bills), Illinois (CURE Act 2025), Connecticut (SB 00191 expansion bill), Maryland (veteran psychedelic program), New Jersey (psilocybin task force), Virginia (psilocybin research), New Mexico (SB 219 medical psilocybin program enacted, not yet operating), DC (Initiative 81)
State has a narrower research carve-out, typically for ibogaine and veterans.
States: Texas ($50M ibogaine research, 2025), Arizona (psilocybin research fund), Kentucky, Utah; 5+ other states with active 2026 bills.
State law mirrors federal Schedule I with no decriminalization or pilot legislation.
States: Alabama, Alaska, Arkansas, Delaware, Florida*, Georgia*, Hawaii, Idaho*, Indiana, Iowa, Kansas, Louisiana, Maine, Minnesota, Mississippi, Missouri, Montana, Nebraska, Nevada, New Hampshire, North Carolina, North Dakota, Ohio, Oklahoma, Pennsylvania, Rhode Island, South Carolina, South Dakota, Tennessee, Vermont, West Virginia, Wisconsin, Wyoming.
* Florida, Georgia, and Idaho also ban psilocybin spores under state law.
Click any highlighted state to read the full legal breakdown. We have deep state pages for the 20 states with the most active reform or largest readerships. Other states default to the federal-law summary above.
Each psychedelic has its own state map. Here is the short version for the five drugs people search for most often. For rules outside the United States, see where psychedelics are legal internationally.
Psilocybin is legal under state law in Oregon and Colorado. About 30 cities have decriminalized — but city decrim is not legal access. For deeper detail, see our "are mushrooms legal" state guide. California residents can check California's status and the pending California psychedelic bills.
MDMA is Schedule I in every US state. No state has legalized or decriminalized MDMA. After the FDA rejected Lykos in August 2024, federal approval is pushed past 2027. See the global MDMA legal map for country-by-country status.
DMT is Schedule I federally. Colorado is the only state with state-level decriminalization. Four DEA-exempted religious organizations may use ayahuasca. See our DMT legal status guide for the four exempted churches and international rules.
Ibogaine is Schedule I federally. Texas allocated $50 million in 2025 for ibogaine research, the largest state investment. Arizona, Kentucky, and Utah have smaller research carve-outs. See our ibogaine guide for the cardiac safety profile.
Ketamine is the only psychedelic legally available nationwide. It is Schedule III and FDA-approved (Spravato for treatment-resistant depression). At-home ketamine telehealth operates in 38+ states. See the ketamine therapy guide.
Three federal shifts and one state shift are the ones to watch.
Oregon and Colorado have legal psychedelic programs open to any adult 21 or older, and New Mexico has enacted a medical-only program that is not yet operating. Oregon's Measure 109 psilocybin service centers have operated since 2023, Colorado's program comes from Prop 122 (the Natural Medicine Health Act, 2022), and New Mexico targets first patient access for December 2026. About 30 US cities have decriminalized psilocybin or all entheogens, but city decrim is not the same as legal access. Ketamine is legal nationwide as Schedule III, and all other classic psychedelics remain Schedule I federally.
Psilocybin is legal under state law only in Oregon (regulated service centers) and Colorado (decriminalized possession plus upcoming healing centers). It is Schedule I and illegal in every other US state, even where individual cities have decriminalized. Click your state in the grid above for the full breakdown.
Decriminalization removes or reduces criminal penalties but does not create legal access. Legalization, in the psychedelic context, means a state has set up a regulated program where adults can legally use the drug in licensed settings. Oregon and Colorado are legal. Cities like Oakland and Detroit are decriminalized.
No. The April 2026 executive order directs federal agencies (FDA, DEA, HHS) to speed up psychedelic drug review and access. It does not change any state law. Oregon and Colorado programs continue under state authority. See our full EO explainer.
About 30 cities across 15+ states have passed deprioritization resolutions. Major ones include Denver, Oakland, Santa Cruz, Washington DC, Somerville, Cambridge, Northampton, Detroit, Ann Arbor, Hazel Park, Seattle, and Berkeley. See the complete list in our cities that decriminalized psilocybin guide.
Not yet, but concrete pathways are already in motion. The April 2026 executive order directs the FDA to issue National Priority Vouchers that shorten review timelines for Breakthrough Therapy-designated psychedelics and creates a Right to Try pathway for investigational use — it accelerates the regulatory process but does not itself reschedule or legalize any substance. See our what psychedelics are legal in the US guide for every pathway currently in motion and why none has resulted in broader legalization as of 2026.
Yes, in Oregon. Measure 109 has no residency requirement — adults 21+ from any US state or country can legally access Oregon's licensed psilocybin service centers. See our Oregon state page for details on out-of-state access and remote preparation support.
Only in Colorado, and with a federal-risk caveat. Colorado's Prop 122 decriminalizes personal cultivation of psilocybin mushrooms for adults 21+ under state law, but growing psilocybin mushrooms remains a federal manufacturing felony everywhere, including Colorado. See our Colorado state page and our psilocybin spores guide for the full cultivation-risk breakdown.
No. Products marketed as "legal psychedelic gummies" or "legal mushroom gummies" in states without legal psilocybin are almost always made with Amanita muscaria, a chemically distinct, unscheduled mushroom — not psilocybin. See our legal psychedelic products guide for the full legal distinction.
Bills move and ballot measures pass. We notify subscribers when a state changes its psychedelic law — no spam, no marketing.
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