Plain-language guide to Ohio’s psilocybin, MDMA, and psychedelic laws — what’s legal, what isn’t, and what may change.
Ohio passed Issue 2 in November 2023 legalizing adult-use cannabis, but that law does not affect psilocybin. Psilocybin mushrooms remain Schedule I under Ohio Revised Code §3719.41 and federal law. No psychedelic decriminalization has passed at the state level. Columbus, Cleveland, and Cincinnati have not passed city-level decriminalization resolutions. HB 249 (2025) proposes a therapeutic pilot but has not advanced.
As of 2026, Ohio does not have a licensed psilocybin access program. Legal options for residents include:
No. Psilocybin is Schedule I under Ohio Revised Code §3719.41. Ohio passed Issue 2 in November 2023 legalizing adult-use cannabis, but that law applies only to marijuana and does not affect psilocybin. No Ohio city has passed a decriminalization or deprioritization resolution for psilocybin mushrooms.
No. Issue 2 (November 2023) legalized recreational cannabis in Ohio. Psilocybin was not mentioned in the measure. Magic mushrooms, psilocybin gummies, and psilocybin edibles all remain Schedule I controlled substances in Ohio.
No. None of Ohio's major cities have passed decriminalization or deprioritization resolutions for psilocybin. Ohio state Schedule I law applies in all of them.
HB 249 (2025) would establish a psilocybin-assisted therapy pilot program in Ohio, and HB 58 (2023) previously proposed psilocybin and MDMA research for PTSD and depression. Neither has passed into law. If HB 249 advances, it would create a research pathway, not general public access.