Six psilocybin retreat centers reviewed across Oregon-licensed service centers, Jamaica, and the Netherlands — licensing, facilitator credentials, integration support, and cost.
Legal psilocybin therapy in the United States is concentrated in two states: Oregon (Measure 109, operational since 2023) and Colorado (Prop 122, healing centers opened 2025). Outside the US, Jamaica and the Netherlands are the primary legal jurisdictions accessible to American travelers. This guide covers the licensed Oregon service centers with public operational histories and the best-documented international options.
We assessed each center on: licensing status (Oregon OHA or applicable jurisdiction), facilitator training and credentials, psychiatric screening protocol, integration support (during and after the session), pricing transparency, and group size. We did not accept paid placement. Oregon centers must complete the OHA licensing process by law; we verified current license status where possible.
InnerTrek was one of the first psilocybin service centers to receive an Oregon OHA license under Measure 109. Co-founded by a trained facilitator and a team with clinical backgrounds, InnerTrek's protocol includes a mandatory preparation session, the psilocybin session itself, and at least one integration session — the minimum required under Oregon law for licensed service centers.
InnerTrek has been involved in psilocybin facilitator training (a key part of the Oregon Measure 109 ecosystem, which requires all facilitators to be licensed) and has published some of its process publicly. The center is in Portland, Oregon's most accessible metro area.
Sana Healing Collective is one of the Southern Oregon licensed psilocybin service centers. Their team emphasizes a trauma-informed, somatic approach — one that considers how the body holds and processes psychological material alongside the psilocybin experience itself.
Sana's facilitators are licensed under Oregon's Measure 109 system. The center offers individual sessions and, in some programs, group formats. Ashland is in Southern Oregon, accessible via Medford (MFR) airport.
EPIC Healing Eugene is an Oregon-licensed service center in Eugene — a University of Oregon city with strong progressive mental health awareness. EPIC has a stated mission around accessibility and has discussed sliding-scale options to reduce the cost barrier for lower-income patients, which is uncommon among licensed Oregon centers.
The center's team includes licensed Oregon facilitators. EPIC has participated in Oregon's public psilocybin policy discussions and has been cited in Oregon media coverage of Measure 109 implementation.
Synthesis Institute launched as a psilocybin truffle retreat in the Netherlands and moved into the Oregon licensed market. Their protocol — built around preparation, experience, and integration as discrete phases — has been referenced in peer-reviewed literature, including a 2023 study in the Journal of Psychopharmacology by Szigeti et al. that documented outcomes across a cohort of Synthesis participants.
Synthesis's Oregon operation extends their Netherlands model with licensed facilitators under Measure 109. Their digital follow-up platform provides structured integration content after the session.
MycoMeditations has operated in Jamaica since 2015 — one of the longest-running English-language psilocybin retreat operations in the world. Psilocybin is not scheduled under Jamaican federal law, which is why retreat operations can function legally there.
MycoMeditations has published participant outcome data in partnership with researchers from Johns Hopkins and other institutions. Their program runs approximately seven days, includes three psilocybin sessions in the first week, and includes integration sessions and post-retreat follow-up calls. Clinical screening is included in the intake process.
Behold Retreats operates luxury psilocybin programs in Jamaica (mushrooms) and the Netherlands (truffles, which are legal there). Their model emphasizes concierge-level access — small groups or private retreats, coach-matched integration, and high-touch follow-up programming.
Behold has documented a structured methodology around life design and integration that goes beyond typical retreat formats. Their intake screening covers medical and psychiatric history. This is a premium-priced option; the trade-off is a more personal experience than high-volume retreat centers.
| Center | Location | Legal status | Sessions per program | Integration included | Approx. cost |
|---|---|---|---|---|---|
| InnerTrek | Portland, OR | Oregon-licensed (OHA) | 1 (+ prep + integration) | Yes — Oregon minimum required | $1,500–$3,000 |
| Sana Healing Collective | Ashland, OR | Oregon-licensed (OHA) | 1 or group | Yes — trauma-informed | $1,200–$2,800 |
| EPIC Healing Eugene | Eugene, OR | Oregon-licensed (OHA) | 1 | Yes | Contact (sliding scale available) |
| Synthesis Institute | Oregon | Oregon-licensed (OHA) | 1 + digital integration | Yes — structured protocol | $2,000–$3,500 |
| MycoMeditations | Jamaica | Legal in Jamaica (not US) | 3 (over 7 days) | Yes — group integration + follow-up | $1,400–$3,500 |
| Behold Retreats | Jamaica / Netherlands | Legal in both jurisdictions | 1–2 (private or group) | Yes — coaching model | $3,000–$8,000+ |
Oregon service centers operate under the most regulated psilocybin framework in the US. OHA-licensed facilitators complete state-approved training and pass background checks. Each session is preceded by a mandatory preparation session and followed by an integration session — these are not optional add-ons under Measure 109, they are legal requirements.
Jamaica's legal status is not the same as US federal law. Psilocybin mushrooms are not criminalized under Jamaican law, but retreat operators are not government-licensed in the same structured way Oregon is. That said, Jamaica-based operators like MycoMeditations have been operating since 2015 with peer-reviewed research partnerships — a longer track record than most Oregon service centers, which only opened in 2023.
The meaningful differences: Oregon keeps you in the US (no passport required, no international travel), operates under a regulatory framework with minimum standards, and allows one-session programs. Jamaica typically offers multiple sessions over several days, often at lower total cost despite international travel, in a natural environment outside a clinical setting.
Best for a regulated US option: InnerTrek or Synthesis (Portland and Oregon, respectively). Both are OHA-licensed and operating under the structured framework that makes Oregon psilocybin distinct from any other US jurisdiction.
Best international value with a published track record: MycoMeditations. Eleven years of operation and peer-reviewed research partnerships set it apart from newer Jamaica competitors.
Best for trauma-specific work: Sana Healing Collective's somatic, trauma-informed approach is the most differentiated from a general-wellness format.
For a broader understanding of the evidence before deciding, read our psilocybin therapy guide. To map your own situation to the right treatment, use our which psychedelic quiz.
Oregon is the only US state with fully operational licensed psilocybin service centers (Measure 109, operational since 2023). Licensed facilitators complete state-mandated training, and service centers are licensed by the Oregon Health Authority (OHA). Colorado passed Prop 122 in 2022, and healing centers began operating in 2025. Psilocybin remains Schedule I in all other US states under both state and federal law.
Psilocybin mushrooms are not included in Jamaica's Dangerous Drugs Act and are not criminalized under Jamaican federal law. This is not the same as being approved or regulated — Jamaica has no licensed psilocybin retreat framework the way Oregon does. Retreat operators in Jamaica function legally in this unregulated space. US citizens who travel to Jamaica for psilocybin therapy are not subject to US law while abroad, though bringing controlled substances back to the US would be illegal.
Oregon psilocybin service center programs typically cost $1,200–$3,500 for a full protocol, which under Oregon law must include at least one preparation session, the psilocybin session itself, and at least one integration session. Facilitator fees, the psilocybin dose, and facility fees are typically bundled. Insurance does not cover psilocybin sessions under any current US insurance plan.
The strongest contraindications for psilocybin are a personal or first-degree family history of schizophrenia, bipolar I disorder, or other psychosis spectrum conditions — psilocybin can precipitate or worsen psychosis in genetically vulnerable individuals. Additional contraindications include lithium (risk of seizures when combined with psilocybin), active suicidality without clinical supervision, and heart conditions that increase the risk from the cardiovascular activation psilocybin causes. MAOIs can prolong and intensify the psilocybin experience. Responsible centers screen for all of these before admission.
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