Oregon Measure 109 licensed psilocybin service center and facilitator training program.
Oregon Measure 109 (licensed service center)
US-licensed psilocybin service centers (Oregon Measure 109 and Colorado Prop 122), plus the more medically-structured international operators for ayahuasca, ibogaine, and 5-MeO-DMT. Inclusion is not endorsement.
Oregon Measure 109 licensed psilocybin service center and facilitator training program.
Oregon-licensed psilocybin services center in Bend operated by licensed facilitators.
First licensed psilocybin service center to open under Measure 109 (May 5, 2023 licensure; first client June 23, 2023). 500+ clients served as of 2025.
The Center Origin (Denver, CO)
The first licensed psilocybin healing center in Colorado under Prop 122 / Natural Medicine Health Act; received license March 31, 2025 and conducted the state's first regulated psilocybin session on June 6, 2025.
Psilocybin Healing Centers of Colorado
Denver-based licensed healing center operated by the team behind My Denver Therapy. Every facilitator is a Clinical Facilitator — state-licensed under Prop 122 AND a licensed mental-health professional (LPC, LMFT, PMHNP) — which is a higher bar than the baseline facilitator credential.
Long-running Jamaican psilocybin retreat with medical screening and group + 1:1 support; one of the earliest commercial operators.
Psilocybin-truffle retreat program in the Netherlands with clinical research collaborations (Imperial College, University Hospital Basel).
Shipibo-tradition ayahuasca retreat in the Peruvian Amazon with long operational history and formal medical screening.
Costa Rica-based Shipibo-tradition ayahuasca retreat with explicit medical screening, on-site medical personnel, and published adverse-event protocols.
Rythmia Life Advancement Center
Larger, wellness-oriented ayahuasca retreat in Costa Rica with medical oversight; more resort-style than traditional.
Medically-supervised ibogaine treatment with cardiac pre-screen (EKG, electrolytes), continuous telemetry, magnesium/potassium loading, and on-site physicians. Among the most medically structured Mexico-based programs.
Ibogaine carries documented cardiac mortality risk; the quality of the cardiac screening and monitoring protocol matters more than any other feature of the retreat.
Partner facility with the Stanford MISTIC trial and Texas IMPACT program; full cardiac-safety protocol; frequently works with veterans groups.
Published outcomes include VERITAS (Veterans Exploring Treatment with Psychedelics) cohort.
One of the few 5-MeO-DMT retreat operators with an explicit screening protocol; uses synthetic 5-MeO-DMT rather than toad-derived secretion, addressing both conservation concerns and purity.
Synthetic sourcing protects the Sonoran Desert toad (Incilius alvarius), which is threatened by over-harvesting for ceremonial use.
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We update this directory as new licensed retreats open and international operators expand.
Underground US ayahuasca circles, unlicensed psilocybin retreats, peyote ceremonies for non-Native participants, and kambo-centered retreats are excluded by policy. This is not a moral judgment on individual practices — it is a product decision about what is defensible to list on a YMYL medical-reference site. If you are considering any of these, the ayahuasca, peyote, and what is kambo and what are the risks? guides contain the harm-reduction context you need.
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